constipation, stomach cramps; lack of sweating, painful or difficult urination, decrease or increase in urination, bed-wetting; joint pain, lower back or side pain; blurred or double vision, difficulty walking, headache, pain in jaw or testicles, pain or numbness in fingers or toes; nervousness, trouble sleeping, confusion, dizziness, fever or chills, hallucinations, loss of appetite, cough, unusual bleeding or bruising, black, tarry stools, blood in urine or stools, small red spots on the skin.

Precautions:

Contraceptive (birth control) measures are recommended for use in men and women while taking this medication.

This medication is not recommended for use in pregnant or nursing women.

If you become pregnant while taking this drug, contact your doctor. This medication can lower your body's ability to fight an infection.

Notify your doctor if you develop any signs of an infection such as fever, sore throat, rash, or chills. Do not have immunizations/vaccinations without consent of your doctor, and avoid contact with people who have recently received oral polio vaccine.

For information on Medic Alert(TM) call 1-800-854-1166. In Canada call 1-800-668-1507.

Generic Name: Vincristine Sulfate

Oncovin 1 mg/ml Vial - Prescription

Vincasar 1 mg/ml Vial - Prescription

Vincristine Sulfate 1 mg/ml Vial - Prescription

Oncovin 1 mg/ml Disposable Syringe - Prescription

Vincristine

Vincristine is a drug used to treat cancer.
You may have redness, pain, warmth, or swelling at the IV site.
This drug may have harmful effects on the unborn child, so effective methods of birth control should be used during your cancer treatment.
Ask your own doctor or health care provider any specific medical questions that you have.
Your mouth care should consist of gently cleaning your teeth or dentures and rinsing your mouth with a mixture of 1/2 teaspoon salt in 8 ounces of water or 1/2 teaspoon sodium bicarbonate (baking soda) in 8 ounces of water.

http://patienteducation.upmc.com/Pdf/Vincristine.pdf
Tell your doctor and pharmacist all the medications you are currently taking. drug, pregnant.

2004-4084B1_04_FDA-Marqibo-errata

On page 4, third paragraph, second sentence, the 3 should be changed to 2.
On page 4, third paragraph, third sentence, the 3 should be changed to 2.
On page 15, in the first Reviewer's Comment: replace this sentence, "The protocol did not stipulate that responses had to be confirmed."
with the following "The first version of the protocol did not stipulate that responses had to be confirmed; however, later versions did."
On page 24, third paragraph under Efficacy Analyses, please delete the first sentence of that paragraph.

http://www.fda.gov/ohrms/dockets/ac/04/briefing/2004-4084B1_04_FDA-Marqibo-errata.pdf
On page 24, third paragraph under Efficacy Analyses, in the fifth sentence change the 10 to 13. third paragraph, Sulfate Liposomes Injection.

therapeutic_1000

A- For the treatment of patients with chronic myeloid leukemia in blast crisis, accelerated phase, or in chronic phase after failure of interferon-alpha therapy.
B- For the treatment of patients with gastrointestinal stromal tumour.

For treatment of adult patients with glioblastoma multiforme or anaplastic astrocytoma, and documented evidence of recurrence or progression after standard therapy (resection, radiotherapy, and chemotherapy). Injection, METHOTREXATE.

jant02i4p202o

An 11-year old girl, diagnosed as a case of lymphoblastic lymphoma was started on continuous Cyclophosphamide, Adriamycin, Vincristine and Prednisolone regimen, she developed hoarseness of voice while on 2nd phase of maintenance therapy.
Direct laryngoscopy revealed right vocal cord palsy.
Laryngeal nerve paralysis induced by Vincristine is a known but rare complication.
Hence we present this case report of an infrequent complication of Vincristine with a review of the literature.

As many patients have primary tumors or metastatic lesions in sites that could cause the clinician to overlook this reversible cause of neurologic dysfunction the potential for misdiagnosis is high. vincristine, diagnosis.